Title list by research areas [Research Profiles 2024]
Life science
- Mechanisms of phloem formation in plants (Department of Biological Sciences, Graduate School of Science, Professor Tatsuo Kakimoto; Assistant Professor Pingping Qian)
- Improving mitochondrial function by controlling mitochondrial DNA movement (Department of Biological Sciences, Graduate School of Science, Professor Naotada Ishihara)
- Development of cancer immunotherapy using antigen glycan (Department of Chemistry, Graduate School of Science, Assistant Professor Yoshiyuki Manabe; Professor Koichi Fukase)
- Control of antibody dynamics and activity by glycan modification (Department of Chemistry, Graduate School of Science, Assistant Professor Yoshiyuki Manabe; Associate Professor Kazuya Kabayama; Professor Koichi Fukase)
- Elucidation of the pumping mechanism of light-driven proton-pumping proteins (Department of Chemistry, Graduate School of Science, Professor Yasuhisa Mizutani)
- Elucidating the ion channel structure of the antibiotic amphotericin B, solving a 50-year-old mystery (Department of Chemistry, Graduate School of Science (currently, Office of Management and Planning), Assistant Professor (currently, Chief Research Administrator) Yuichi Umegawa; Department of Chemistry, Graduate School of Science, Professor Michio Murata)
- Towards the development of safe and effective therapeutic antisense oligonucleotides (Laboratory of Bioorganic Chemistry, Graduate School of Pharmaceutical Sciences, Associate Professor Takao Yamaguchi; Professor Satoshi Obika)
- Switching off specific brain cells protects against stress (Drug Innovation Center, Graduate School of Pharmaceutical Sciences, Associate Professor Atsushi Kasai; Laboratory of Molecular Neuropharmacology, Graduate School of Pharmaceutical Sciences, Professor Hitoshi Hashimoto)
- New insights into the mechanism underlying muscle hypertrophy during resistance training (Laboratory of Stem Cell Regeneration and Adaptation, Graduate School of Pharmaceutical Sciences, Professor So-ichiro Fukada)
- Site-selective and multiple deuteration and application to drug discovery (Synthetic Medical Chemistry, Graduate School of Pharmaceutical Sciences, Associate Professor Yoshinari Sawama; Professor Shuji Akai)
- Improvement of tumor targeting efficiency of nanoparticles in combination with oncolytic reovirus (Laboratory of Biochemistry and Molecular Biology, Graduate School of Pharmaceutical Sciences, Associate Professor Fuminori Sakurai)
- Discovery of fibroblastic reticular cells that regulate body cavity-associated lymphoid tissues (Immunology Frontier Research Center, Specially Appointed Associate Professor Yasutaka Okabe)
- The COMMD3/8 complex: a novel therapeutic target for autoimmune diseases (Laboratory of Immune Response Dynamics, Immunology Frontier Research Center, Professor Kazuhiro Suzuki)
- Identification and developmental regulation of long-lived plasma cells (Regulation of Host Defense Team, Center for Infectious Disease Education and Research, Professor Wataru Ise)
- Niche cells essential for hematopoietic stem cell maintenance and hematopoiesis and adipo-osteogenesis in bone marrow (Graduate School of Frontier Biosciences/Graduate School of Medicine/Immunology Frontier Research Center, Distinguished Professor Takashi Nagasawa; Associated Professor Yoshiki Omatsu)
- Novel function of HP1, a protein responsible for chromosome aggregation (Laboratory of Epigenome Dynamics, Graduate School of Frontier Bioscience, Specially Appointed Assistant Professor Ryo Maeda; Professor Makoto Tachibana)
- Development of regenerative therapies using iPS cell-derived cartilage (Department of Biochemistry and Molecular Biology, Graduate School of Medicine, Assistant Professor Kengo Abe; Specially Appointed Assistant Professor Nobuyuki Shima; Professor Noriyuki Tsumaki)
- Elucidation of the enteric metabolic exacerbation of periodontal disease in diabetes and the mechanism of enhanced gluconeogenesis (Department of Periodontology, Graduate School of Dentistry, Professor Shinya Murakami; Assistant Professor Yoichiro Kashiwagi)
- Injectable prevascularized mature adipose tissues (iPAT) to achieve long-term survival in soft tissue regeneration (Joint Research Laboratory (TOPPAN) for Advanced Cell Regulatory Chemistry, Graduate School of Engineering, Specially Appointed Assistant Professor Fiona Louis)
- Development of versatile fluorescent protein labeling probes for live-cell imaging (Department of Applied Chemistry, Graduate School of Engineering, Professor Kazuya Kikuchi; Associate Professor Masafumi Minoshima)
- Pathophysiology of sensory abnormality in Autism Spectrum Disorders (United Graduate School of Child Development, Associate Professor Kuriko Kagitani-Shimono; Specially Appointed Professor Masako Taniike)
- Development of approaches to promote personalized medicine in trauma care (Department of Traumatology and Acute Critical Medicine, Graduate School of Medicine, Specially Appointed Assistant Professor Jotaro Tachino; Specially Appointed Assistant Professor Hisatake Matsumoto)
- Collaborative research with local governments to prevent the need for long-term care and promote healthy community development (Division of Health Sciences, Graduate School of Medicine, Professor Mai Kabayama; Specially Appointed Assistant Professor Yaya Li)
- Identification of the mechanism by which thymoma implicates autoimmune neuromuscular diseases, including myasthenia gravis (Department of Neurology, Graduate school of Medicine, Associate Professor Tatsusada Okuno; Department of Frontier Research in Tumor Immunology, Graduate school of Medicine, Specially Appointed Professor Naganari Ohkura; Department of Neurology, Graduate school of Medicine, Professor Hideki Mochizuki)
- Development of a fluorescent sensor for real-time recording of oxytocin dynamics in the brain (Department of Pharmacology, Graduate School of Medicine, Specially Appointed Lecturer Daisuke Ino; Professor Hiroshi Hibino)
- Molecular mechanisms of electrochemical conversion in voltage-sensing phosphatase (VSP) (Integrative Physiology, Graduate School of Medicine, Specially Appointed Assistant Professor Natsuki Mizutani; Professor Yasushi Okamura)
- Software development in single-cell RNA data analysis considering pseudotime (Department of RNA Biology and Neuroscience, Graduate School of Medicine, Associate Professor Yuki Kato)
- The study on cognitive impairment in hypertensive individuals in ambulatory care (Cherry study) (Department of Geriatric and General Medicine, Graduate School of Medicine, Professor Koichi Yamamoto; Professor Emeritus Hiromi Rakugi)
- Therapeutic implication for regulation of immune cells via tumor vessels (Osaka University Hospital, Associate Professor Takehiro Noda; Department of Gastroenterological Surgery, Graduate School of Medicine, Associate Professor Shogo Kobayashi; Professor Hidetoshi Eguchi)
- Prediction of therapeutic effect of combined immunotherapy using tumor microenvironment analysis and MRI images of hepatocellular carcinoma (Department of Gastroenterology and Hepatology, Graduate School of Medicine, Assistant Professor Takahiro Kodama; Professor Tetsuo Takehara)
- Development of therapeutic strategy for Crohn’s disease by targeting microbiota-derived metabolites (Institute for Advanced Co-Creation Studies, Associate Professor Hisako Kayama; Department of Microbiology and Immunology, Graduate School of Medicine, Professor Kiyoshi Takeda)
- Prognostic significance of the HFA-PEFF score in patients with heart failure with preserved ejection fraction (Department of Cardiovascular Medicine, Graduate School of Medicine, Specially Appointed Assistant Professor Yohei Sotomi; Professor Yasushi Sakata)
- Phosphatidylinositol‑3,4,5‑trisphosphate interacts with alpha‑synuclein and initiates its aggregation and formation of Parkinson’s disease‑related fibril polymorphism (Department of Neurology, Graduate school of Medicine, Assistant Professor Kensuke Ikenaka; Professor Hideki Mochizuki)
- Identification of a causative gene for dilated cardiomyopathy and future precision medicine (Department of Cardiology, Graduate School of Medicine, Assistant Professor Hidetaka Kioka; Associate Professor Yoshihiro Asano; Professor Yasushi Sakata)
- Generation of 3D lacrimal gland organoids from human pluripotent stem cells (Department of Stem Cells and Applied Medicine, Graduate School of Medicine, Professor Ryuhei Hayashi)
- Development of a novel cancer immunotherapy by targeting regulatory T cells (Department of Frontier Research in Tumor Immunology, Graduate School of Medicine, Specially Appointed Professor Naganari Ohkura)
- Automated neuromagnetic examination of epilepsy using deep learning (Department of Neurological Diagnosis and Restoration, Graduate School of Medicine, Specially Appointed Professor Masayuki Hirata; Visiting Researcher Ryoji Hirano)
- Development of the method for identifying drug resistance gene from Malaria parasites (Department of Molecular protozoology, Research Institute for Microbial Diseases, Professor Shiroh Iwanaga)
- Elucidation of the mechanism of the disruption of the crosstalk between host and gut microbiota with aging (Department of Molecular Microbiology, Research Institute for Microbial Diseases, Associate Professor Shimpei Kawamoto; Professor Eiji Hara)
- Discovery of protein degraders targeting a multi-functional protein (Department of Complex Molecular Chemistry, SANKEN (The Institute of Scientific and Industrial Research), Associate Professor Yukihiro Itoh)
- Development of a fast-responding genetically-encoded temperature indicator (Department of Biomolecular Science and Engineering, SANKEN (The Institute of Scientific and Industrial Research), Specially Appointed Associate Professor Tetsuichi Wazawa; Specially Appointed Researcher Kai Lu; Professor Takeharu Nagai)
- Elucidating the mechanism of NLRP3 inflammasome activity regulation by lysosomes (Department of Respiratory Medicine and Clinical Immunology, Graduate School of Medicine, Specially Appointed Assistant Professor Kohei Tsujimoto; Professor Atsushi Kumanogoh)
- Evidence-based prediction of cellular toxicity for amorphous silica nanoparticles (Graduate School of Pharmaceutical Science, Doctoral Student Martin; Institute for Protein Research, Laboratory for Computational Biology, Assistant Professor Reiko Watanabe; Professor Kenji Mizuguchi)
Telecommunications
Nanotechnologies / Materials
- Molecular recognition of polysaccharide derivatives with highly branched architecture (Department of Macromolecular Science, Graduate School of Science, Professor Ken Terao)
- Fixation of CO2 as a C1 source into organic compounds catalyzed by lanthanide metal complexes (Department of Materials Engineering Science, Graduate School of Engineering Science, Associate Professor Hayato Tsurugi)
- Control of the surface electronic structure of topological Kondo insulators (Department of Frontier Biosciences, Graduate School of Frontier Biosciences, Professor Shin-ichi Kimura)
- Development of the Hydrodefluorination reaction of perfluoroalkyl substances (Department of Applied Chemistry, Graduate School of Engineering, Assistant Professor Ryohei Doi)
- Stereospecific cyanodifunctionalization of alkenes (Department of Applied Chemistry, Graduate School of Engineering, Assistant Professor Kensuke Kiyokawa)
- Wavelength-recognizable novel Sb-chalcohalide photodiode (Department of Applied Chemistry, Graduate School of Engineering/Innovative Catalysis Science Division, Assistant Professor Ryosuke Nishikubo; Department of Applied Chemistry, Graduate School of Engineering, Ph.D Student Shaoxian Li; Department of Applied Chemistry, Graduate School of Engineering/Innovative Catalysis Science Division, Professor Akinori Saeki)
- Efficient and facile induction of room-temperature phosphorescence by confinement of luminescent molecules in heavy atom spaces (Department of Applied Chemistry, Graduate School of Engineering, Professor Norimitsu Tohnai)
- Development of single-carbon atom doping reactions (Department of Applied Chemistry, Graduate School of Engineering, Professor Mamoru Tobisu; Assistant Professor Hayato Fujimoto)
- Development of room temperature phosphorescence materials with naturally abundant element (Department of Applied Chemistry, Graduate School of Engineering, Associate Professor Youhei Takeda)
- Development of multicomponent covalent organic frameworks (Division of Applied Chemistry, Graduate School of Engineering, Associate Professor Mitsuharu Suzuki)
- Synthesis and characterization of bis-periazulene: Unprecedented pyrene’s structural isomer (Department of Applied Chemistry, Graduate School of Engineering, Assistant Professor Akihito Konishi)
- Development of co-crystalline organic materials with arbitrary composition ratio (Department of Materials Engineering Science, Graduate School of Engineering Science, Professor Ichiro Hisaki; Assistant Professor Ryusei Oketani)
- Triplet diradical cation with near-infrared emission (Department of Materials Engineering Science, Graduate School of Engineering Science, Associate Professor Akihiro Shimizu; Professor Ryo Shintani)
- Nanosheet synthesis using liquid crystals as templates (Department of Materials Engineering Science, Graduate School of Engineering Science, Associate Professor Yoshiaki Uchida)
- Development of thermal switch material using structure change in organic film including nanostructure (Department of System Innovation, Graduate School of Engineering Science, Professor Yoshiaki Nakamura; Assistant Professor Takafumi Ishibe)
- Lead-free solders reinforced with ceramic particles (Joining and Welding Research Institute, Professor Hiroshi Nishikawa)
- Development of non-fused acceptor materials toward organic solar cells (Department of Soft Nanomaterials, SANKEN (The Institute of Scientific and Industrial Research), Assistant Professor Seihou Jinnai; Professor Yutaka Ie)
- Find rare events at single-molecule level (Department of Bionanotechnology, SANKEN (The Institute of Scientific and Industrial Research), Assistant Professor Yuki Komoto; Professor Masateru Taniguchi)
- Wood-derived semiconducting nanomaterials with customizable 3D structures and functions (Department of Functionalized Natural Materials, SANKEN (The Institute of Scientific and Industrial Research), Associate Professor Hirotaka Koga)
- Electrodeposition of nanocellulose for multiscale structuring (Department of Functionalized Natural Materials, SANKEN (The Institute of Scientific and Industrial Research), Assistant Professor Takaaki Kasuga)
- Failure mechanisms of the bonded interface between mold epoxy and metal substrate exposed to high temperature (SANKEN (The Institute of Scientific and Industrial Research), Specially Appointed Associate Professor Chuantong Chen; Specially Appointed Professor Katsuaki Suganuma)
- Development of ultrafast electric field measurement around electric beam and charged particles ~First experimental demonstration of relativistic Coulomb electric field contraction~ (Institute of Laser Engineering, Associate Professor Makoto Nakajima )
- Terahertz emission spectroscopy for advanced electronic materials and devices~from phenomenology to quantitative analysis~ (Institute of Laser Engineering, Professor Masayoshi Tonouchi)
- Achieving near-isotropic high tensile performance in additively manufactured Ti through interstitial solute influences (Joining and Welding Research Institute, Specially Appointed Assistant Professor Ammarueda Issariyapat; Professor Junko Umeda)
- Synthesis and function of nanosheets doped with multi-elements in equal molarity (Joining and Welding Research Institute, Professor Hiroya Abe; Specially Appointed Researcher Fei Li)
Energy
Manufacturing technologies
- Ultrastable long-duration super-resolution Raman microscopy (Institute for Advanced Co-Creation Studies/Department of Applied Physics, Graduate School of Engineering, Associate Professor Takayuki Umakoshi; Department of Applied Physics, Graduate School of Engineering Professor Prabhat Verma)
- Advanced life extension technology based on digital twins for steel structures: Highly accurate prediction of cyclic elastoplastic deformation and fatigue damage process against earthquake and traffic loads (Department of Civil Engineering, Graduate School of Engineering, Associate Professor Seiichiro Tsutsumi)
- High-yield bioactive triterpenoid production by heterologous expression of biosynthetic genes in Nicotiana benthamiana (Department of Biotechnology, Graduate School of Engineering, Associate Professor Hikaru Seki)
- Palladium-catalyzed skeletal rearrangement of cyclobutanones (Department of Applied Chemistry, Graduate School of Engineering, Assistant Professor Yusuke Ano)
- Unified catalysis concepts from molecular design to sustainable chemicals and materials (Department of Applied Chemistry, Graduate School of Engineering, Professor Takashi Hayashi)
- High-efficiency ultra-precision polishing technique for diamond substrates using plasma (Research Center for Precision Engineering, Graduate School of Engineering, Professor Kazuya Yamamura)
- Research on creation of ultra-flexible and highly transparent electronics (Department of Advanced Materials and Implementations, SANKEN (The Institute of Scientific and Industrial Research), Associate Professor Teppei Araki)
- Initiation mechanism of pitting corrosion in weld heat affected zone of duplex stainless steel (Department of Joining Metallurgical Evaluation, Joining and Welding Research Institute, Assistant Professor Yuyang Hou)
- Joint strength and numerical modelling of laser welding for CFRP/Steel and resistance spot welding for CFRP/Aluminum (Research Division of Materials Joining Assessment, Joining and Welding Research Institute, Professor Ninshu Ma)
- Visualization study on dissimilar Friction Stir Welding (FSW) technology for lightweight structural manufacturing (Research Division of Materials Joining Assessment, Joining and Welding Research Institute, Specially Appointed Associate Professor Peihao Geng; Professor Ninshu Ma)
Social innovation
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